abstract：OBJECTIVE:Femoral nerve block (FNB) is increasingly used as an analgesic modality in patients with femoral fracture both in the emergency department and preoperatively. We describe an occurrence of unexpected dislocation of the fracture after FNB. CASE REPORT:An FNB was administered to treat pain in a 48-year-old pati...

journal_title：Regional anesthesia and pain medicine

authors： Marić S,Robinson A,Vandepitte C,Hadzic A

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Many patients experience moderate to severe postoperative pain. Nitrous oxide (N₂O) exerts analgesia by inhibition of N-methyl-D-aspartate receptors. Ketamine, another N-methyl-D-aspartate receptor antagonist, reduces postoperative opioid consumption and pain. A similar effect of N₂O is plausi...

journal_title：Regional anesthesia and pain medicine

authors： Duma A,Helsten D,Brown F,Bottros MM,Nagele P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Despite ultrasound (US) guidance, sciatic nerve block (SNB) remains among the least performed peripheral blocks. By targeting the tissue plane between the gluteus maximus and quadratus femoris muscles, the US-guided subgluteal space technique may facilitate the performance of US-guided SNB. We...

journal_title：Regional anesthesia and pain medicine

authors： Abdallah FW,Chan VW,Koshkin A,Abbas S,Brull R

更新日期：2013-11-01 00:00:00

abstract：:The introduction of ultrasound guidance for regional anesthesia has resulted in an explosion of interest in its use for postoperative analgesia, particularly for orthopedic surgery. Regional anesthesia demonstrates unequivocal superiority compared with systemic opioids with respect to analgesia, reduced opioid consump...

journal_title：Regional anesthesia and pain medicine

authors： Choi S,Trang A,McCartney CJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Third occipital nerve block (TONB) is commonly used in the diagnosis and treatment of upper neck pain and cervicogenic headaches. Although fluoroscopy is the current imaging standard for TONB, ultrasound (US) guidance offers a promising, radiation-free alternative. In this randomized, observer-blinded trial,...

journal_title：Regional anesthesia and pain medicine

authors： Finlayson RJ,Etheridge JP,Vieira L,Gupta G,Tran DQ

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A sublingual sufentanil tablet is being developed as a potential alternative to intravenous (IV) opioids for the management of postoperative pain. The objective of these studies was to evaluate the pharmacokinetics, efficacy, and safety of sublingual sufentanil tablets for postoperative pain m...

journal_title：Regional anesthesia and pain medicine

authors： Minkowitz HS,Singla NK,Evashenk MA,Hwang SS,Chiang YK,Hamel LG,Palmer PP

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Ivor-Lewis esophagectomy is associated with significant postoperative analgesic requirements and perioperative complications. A dual-epidural technique may improve perioperative outcomes compared with single thoracic epidural analgesia. METHODS:This study identified all cases of Ivor-Lewis esophagectomy ove...

journal_title：Regional anesthesia and pain medicine

authors： Brown MJ,Kor DJ,Allen MS,Kinney MO,Shen KR,Deschamps C,Nichols FC,Mauck WD,Mantilla CB

更新日期：2013-01-01 00:00:00

abstract：:Shoulder surgery is associated with significant postoperative pain in many patients. The use of an interscalene nerve block offers good analgesia but is associated with a high incidence of an ipsilateral phrenic nerve block. Several strategies to avoid this adverse effect have been studied. Possible strategies are (1)...

journal_title：Regional anesthesia and pain medicine

authors： Verelst P,van Zundert A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Recent clinical trials suggest that subfascial (sometimes termed subepineural) injections result in faster block onset and success compared with conventional techniques. This prospective, randomized, observer-blinded study measured and compared the 3-dimensional spread pattern and volume of pe...

journal_title：Regional anesthesia and pain medicine

authors： Missair A,Weisman RS,Suarez MR,Yang R,Gebhard RE

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The duration of nerve block is longer in streptozotocin (STZ)-induced diabetic rats for all local anesthetics (with and without adjuvants) compared with normal rats. Perioperative glycemic control is currently practiced to reduce adverse events in many at-risk patients, especially in diabetic ...

journal_title：Regional anesthesia and pain medicine

authors： Kroin JS,Buvanendran A,Tuman KJ,Kerns JM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pregabalin is often used as a perioperative analgesic adjunct; some studies show benefit, but others do not. Adverse effects, such as confusion and sedation, have been attributed to perioperative use of pregabalin. We tested the hypothesis that pregabalin, when used as part of a multimodal ana...

journal_title：Regional anesthesia and pain medicine

authors： Yadeau JT,Paroli L,Kahn RL,Jules-Elysee KM,Lasala VR,Liu SS,Lin E,Powell K,Buschiazzo VL,Wukovits B,Roberts MM,Levine DS

更新日期：2012-05-01 00:00:00

abstract：:This article provides a brief overview of earlier work of our group on the peripheral signaling of pain, summarizes more recent studies on the role of opioids in chronic neuropathic pain, and speculates on the future of gene-based therapies as novel strategies to enhance the peripheral modulation of pain. Neurophysiol...

journal_title：Regional anesthesia and pain medicine

authors： Raja SN

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anesthesia and analgesia with paravertebral block are reportedly variable. Existence of an endothoracic fascia has been proposed as one of the possible mechanisms leading to variability. We undertook an electron-microscopy imaging study to investigate the endothoracic fascia in the thoracic pa...

journal_title：Regional anesthesia and pain medicine

authors： Stopar Pintaric T,Veranic P,Hadzic A,Karmakar M,Cvetko E

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Neosaxitoxin (NeoSTX) is a potent site-1 sodium-channel blocker being developed as a local anesthetic. Doses of 100 μg have been used by local infiltration in anesthetized adult humans without adverse effect. We hypothesized that similar doses could cause significant respiratory, neuromuscular, and cardiovas...

journal_title：Regional anesthesia and pain medicine

authors： Wylie MC,Johnson VM,Carpino E,Mullen K,Hauser K,Nedder A,Kheir JN,Rodriguez-Navarro AJ,Zurakowski D,Berde CB

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Use of nonsteroidal anti-inflammatory drug (NSAIDs) analgesics is controversial because of cardiovascular risk, but perioperative use may be advantageous for total joint replacement. Thus, we performed this single-center observational cohort study to determine any association between NSAID use...

journal_title：Regional anesthesia and pain medicine

authors： Liu SS,Bae JJ,Bieltz M,Ma Y,Memtsoudis S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Success in performing ultrasound-guided peripheral nerve blockade (PNB) demands sound knowledge of sonoanatomy, good scanning techniques, and proper hand-eye coordination. The objectives of our study were to evaluate whether simulator training aids success of novice operators in ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： Niazi AU,Haldipur N,Prasad AG,Chan VW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Practitioners mix faster-onset, intermediate-duration local anesthetics (LAs) with slower-onset, long-duration LAs to get fast peripheral nerve block (PNB) onset and long duration. We hypothesized that 1.5% mepivacaine (with epinephrine) (mepivacaine) or 1.5% mepivacaine (with epinephrine) mix...

journal_title：Regional anesthesia and pain medicine

authors： Laur JJ,Bayman EO,Foldes PJ,Rosenquist RW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Complications resulting from vascular penetration during nerve blocks are rare but potentially devastating events that can occur despite meticulous technique. In this in vivo human pilot study, we investigated the potential for detecting vascular penetration with optical reflectance spectrosco...

journal_title：Regional anesthesia and pain medicine

authors： Balthasar A,Desjardins AE,van der Voort M,Lucassen GW,Roggeveen S,Wang K,Bierhoff W,Kessels AG,Sommer M,van Kleef M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Central sensitization is often seen in chronic pain. A relevant and potent mechanism of central sensitization is the central integration of nociceptive impulses. Temporal summation in humans and the wind-up process in animals share common features of central integration. This preclinical and c...

journal_title：Regional anesthesia and pain medicine

authors： Arendt-Nielsen L,Mansikka H,Staahl C,Rees H,Tan K,Smart TS,Monhemius R,Suzuki R,Drewes AM

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transversus abdominis plane (TAP) blocks have been shown to reduce postoperative pain after various abdominal surgical procedures in several studies. The motor nerves of the abdominal wall are located in the same plane as the sensory nerves affected by the TAP block. The aim of this study was ...

journal_title：Regional anesthesia and pain medicine

authors： Petersen M,Elers J,Børglum J,Belhage B,Mortensen J,Maschmann C

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Although infrequent, subdural block is a complication of epidural anesthesia with obvious implications. Knowledge of the spinal subdural compartment (dura-arachnoid interface) may help elucidate controversies arising from evidence that subdural catheter placement is feasible and may be difficult to identify ...

journal_title：Regional anesthesia and pain medicine

authors： Reina MA,Collier CB,Prats-Galino A,Puigdellívol-Sánchez A,Machés F,De Andrés JA

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Detailed description of the tasks anesthetists undertake during the performance of a complex procedure, such as ultrasound-guided peripheral nerve blockade, allows elements that are vulnerable to human error to be identified. We have applied 3 task analysis tools to one such procedure, namely, ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： O'Sullivan O,Aboulafia A,Iohom G,O'Donnell BD,Shorten GD

更新日期：2011-09-01 00:00:00

abstract：:The past century has seen immense progress in the advancement of methodology to evaluate efficacy of treatment interventions for acute and chronic pain. Continuing challenges revolve around how to best select and measure primary efficacy outcomes for a given analgesic trial. Recognizing the complex, multidimensional, ...

journal_title：Regional anesthesia and pain medicine

authors： Gilron I,Jensen MP

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Ultrasound (US) guidance, in some instances, can increase the success rate and reduce the onset and procedure times for peripheral nerve blockade compared with traditional nerve localization techniques. The presumptive mechanism for these benefits is the ability to accurately inject local anesthetic circumfe...

journal_title：Regional anesthesia and pain medicine

authors： Brull R,Macfarlane AJ,Parrington SJ,Koshkin A,Chan VW

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Although complications of the epidural technique are known to affect the fetus adversely, there are no data indicating that regional analgesia directly causes harmful effects to the fetus. Our purpose was to determine the effect of epidural labor analgesia on the Doppler velocimetric indices of the uterine an...

journal_title：Regional anesthesia and pain medicine

authors： Chen LK,Yang YM,Yang YH,Lee CN,Chen SS,Sun WZ

更新日期：2011-05-01 00:00:00

abstract：:The progression of sensory blockade in the hand following a forearm Bier block with ropivacaine is currently unknown. The hands of 10 healthy adult human subjects were anesthetized with ropivacaine, and their sensitivities to cold and touch were tested until the completion of anesthesia. On average, insensitivity to c...

journal_title：Regional anesthesia and pain medicine

authors： Horn JL,Cordo P,Künster D,Harvey C,Cherry A,Bratt A,Gurfinkel V

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Previously, we have demonstrated that extending a continuous femoral nerve block (cFNB) from overnight to 4 days after total knee arthroplasty (TKA) provides clear benefits during the infusion, but not subsequent to catheter removal. However, there were major limitations in generalizing the results of that i...

journal_title：Regional anesthesia and pain medicine

authors： Ilfeld BM,Shuster JJ,Theriaque DW,Mariano ER,Girard PJ,Loland VJ,Meyer S,Donovan JF,Pugh GA,Le LT,Sessler DI,Ball ST

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Subarachnoid blocks are considered routine anesthetic procedures important in the daily practices of most anesthesiologists. However, few data exist regarding modern failure rates or quality-compromising behaviors. METHODS:Sixty adult patients having orthopedic surgery under spinal anesthesia were enrolled ...

journal_title：Regional anesthesia and pain medicine

authors： Weed J,Finkel K,Beach ML,Granger CB,Gallagher JD,Sites BD

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:This prospective, randomized, observer-blinded study compared ultrasound guidance and the conventional landmark-based technique for superficial cervical plexus blockade. METHODS:Forty patients were randomly allocated to receive a block of the superficial cervical plexus using ultrasound guidance (n = 20) or...

journal_title：Regional anesthesia and pain medicine

authors： Tran DQ,Dugani S,Finlayson RJ

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ischemic preconditioning of tissue that is to undergo procedure-induced underperfusion has been used in a number of surgical settings to reduce the subsequent inflammatory response and its sequelae. The objective of this prospective, randomized study was to evaluate the effect of ischemic prec...

journal_title：Regional anesthesia and pain medicine

authors： Memtsoudis SG,Valle AG,Jules-Elysse K,Poultsides L,Reid S,Starcher B,Ma Y,Sculco TP

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to compare the potency of bupivacaine, ropivacaine, and levobupivacaine in an equal dose and concentration for sympathetic block. METHODS:We measured mean arterial pressure, heart rate (HR), and right and left brachial artery blood flow (BABF) before and after cervic...

journal_title：Regional anesthesia and pain medicine

authors： Hashimoto T,Iwasaki T,Takahashi Y,Kimura Y,Nagao M,Yamaguchi S,Hamaguchi S,Kitajima T

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:We present an occurrence of a severe but transient neurologic complication after intraneural injection during an ultrasound-guided interscalene block. CASE REPORT:A 36-year-old man underwent ultrasound-guided interscalene nerve blockade before shoulder incision and drainage. On postoperative day 1, he exhibi...

journal_title：Regional anesthesia and pain medicine

authors： Cohen JM,Gray AT

更新日期：2010-07-01 00:00:00

abstract：:The use of ultrasound to facilitate regional anesthesia is an evolving area of clinical, education, and research interests. As our community's experience grows, it has become evident that anesthesiologists performing "routine" ultrasound-guided blocks may very well be confronted with atypical or even pathologic anatom...

journal_title：Regional anesthesia and pain medicine

authors： Sites BD,Macfarlane AJ,Sites VR,Naraghi AM,Chan VW,Antonakakis JG,Singh M,Brull R

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Lipid infusion reverses systemic local anesthetic toxicity. The acceptable upper limit for lipid administration is unknown and has direct bearing on clinical management. We hypothesize that high volumes of lipid could have undesirable effects and sought to identify the dose required to kill 50% of the animal...

journal_title：Regional anesthesia and pain medicine

authors： Hiller DB,Di Gregorio G,Kelly K,Ripper R,Edelman L,Boumendjel R,Drasner K,Weinberg GL

更新日期：2010-03-01 00:00:00

abstract：:This article qualitatively assesses and summarizes randomized, controlled studies regarding benefits of ultrasound (US) for brachial plexus block and also examines those studies that have compared different brachial plexus block techniques using US.Studies were identified by a search of PUBMED and EMBASE databases usi...

journal_title：Regional anesthesia and pain medicine

authors： McCartney CJ,Lin L,Shastri U

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The typical blind insertion of a catheter into the epidural space risks catheter misplacement into the intrathecal space. The epidural stimulation test is designed to confirm the correct epidural location of a catheter but may also detect unintended intrathecal catheter placement by evaluating...

journal_title：Regional anesthesia and pain medicine

authors： Sutherland MA,Viscomi CM,Dominick TS,Anderson EL

更新日期：2009-11-01 00:00:00

abstract：:Abrupt cessation of intrathecal baclofen (ITB) administration can cause a life-threatening withdrawal syndrome that requires prompt diagnosis and urgent treatment. The current therapy for this condition is administration of propofol, benzodiazepines, paralytics and supportive care. This study reports a 53-year-old pat...

journal_title：Regional anesthesia and pain medicine

authors： Bellinger A,Siriwetchadarak R,Rosenquist R,Greenlee JD

更新日期：2009-11-01 00:00:00

abstract：:As the epidemics of obesity and diabetes expand, there are more patients with these disorders requiring elective surgery. For surgery on the extremities, peripheral nerve blocks have become a highly favorable anesthetic option when compared with general anesthesia. Peripheral blocks reduce respiratory and cardiac stre...

journal_title：Regional anesthesia and pain medicine

authors： Williams BA,Murinson BB,Grable BR,Orebaugh SL

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The perception of high resistance during injection of a local anesthetic during regional anesthesia may indicate intraneural injection. Anesthetists' ability to detect high resistance by "syringe feel" has been questioned in the past. The aim of our study was to investigate the anesthetist's ability to detec...

journal_title：Regional anesthesia and pain medicine

authors： Theron PS,Mackay Z,Gonzalez JG,Donaldson N,Blanco R

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The transarterial axillary block and the ultrasound-guided infraclavicular block are both effective methods of anesthetizing the upper extremity. This study compares these methods with respect to subjective postoperative dysesthesias, block adequacy, patient comfort, and patient satisfaction. ...

journal_title：Regional anesthesia and pain medicine

authors： Tedore TR,YaDeau JT,Maalouf DB,Weiland AJ,Tong-Ngork S,Wukovits B,Paroli L,Urban MK,Zayas VM,Wu A,Gordon MA

更新日期：2009-07-01 00:00:00